From molecules to mastication: the development and evolution of teeth.
نویسندگان
چکیده
Teeth are unique to vertebrates and have played a central role in their evolution. The molecular pathways and morphogenetic processes involved in tooth development have been the focus of intense investigation over the past few decades, and the tooth is an important model system for many areas of research. Developmental biologists have exploited the clear distinction between the epithelium and the underlying mesenchyme during tooth development to elucidate reciprocal epithelial/mesenchymal interactions during organogenesis. The preservation of teeth in the fossil record makes these organs invaluable for the work of paleontologists, anthropologists, and evolutionary biologists. In addition, with the recent identification and characterization of dental stem cells, teeth have become of interest to the field of regenerative medicine. Here, we review the major research areas and studies in the development and evolution of teeth, including morphogenesis, genetics and signaling, evolution of tooth development, and dental stem cells.
منابع مشابه
P-201: The Role of P53 Family Members in Infertility
Background: P53, p63, and p73 transcription factors which are belong to The p53 family, are conserved during evolution. They have important roles in many molecular and cellular functions, including tumor suppression, the development of epithelial cell layers, and the development of central nervous system and immune system. Studies show these molecules also have role in maintaining the genomic i...
متن کاملGene Expression Profile Analysis during Mouse Tooth Development
Introduction: Complex molecular pathways involve in development of different tissues such as teeth. Differential gene expression patterns during teeth development generates different tooth types. Teeth development results from interactions between oral epithelium and underlying ectomesenchyme cells with neural crest origin. Teeth development are regulated by different signaling networks. In thi...
متن کاملEvaluation of mothers’ awareness about the presence of first permanent molar teeth among the 6-8 year old children in Yasuj, Iran, 2016
BACKGROUND AND AIM: First permanent molar teeth (FPMT) erupt slowly and without any side effects among the 6-8 year old children. Sweet snacks consumption, parents’ unawareness about existence of these teeth and lack of attention to oral health care cause early caries among children in these ages. First permanent molars (FPMs) have a very important role in oral cavity among children. Therefore,...
متن کاملThe role of environments with extreme ecological conditions in the reductive evolutionary development processes of animal
Different groups of animals show phenotypic characters, which have been resulted by the reductive phenomena. The examples are the absence of pigmentation; dwindle of eyes in some cave-living animals, and also the absence of scale in some fishes. These characters are often leaded to evolution of new species with special adaptation that is so called "Regressive evolution". The reductive phenomena...
متن کاملAnatomical, functional, physiological and behavioural aspects of the development of mastication in early childhood
Mastication efficiency is defined as the efficiency of crushing food between the teeth and manipulating the resulting particles to form a swallowable food bolus. It is dependent on the orofacial anatomical features of the subject, the coordination of these anatomical features and the consistency of the food used during testing. Different measures have been used to indirectly quantify masticatio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Wiley interdisciplinary reviews. Developmental biology
دوره 2 2 شماره
صفحات -
تاریخ انتشار 2013